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Learn how Lilli Health is shaping the future of PCOS wellness. Learn More

Our Science

PILOT Study

Our first study in 24 patients showed average weight loss of 19 lbs in only 8 weeks with a 52% reduction in fasting insulin and more than 50% drop in HOMA-IR.

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METABOLIC Study

This study demonstrated a dramatic increase in fat oxidation due to a 52% reduction in fasting insulin levels.

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Randomized Controlled Trial (RCT)

This independent RCT revealed significant reductions in weight, BMI, and waist circumference across both video education and face-to-face groups.

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Case Series

An independent case series found that a Low Insulin Lifestyle improved menstrual regularity and led to conception within an average of 86 days in previously infertile women with obesity—without the use of fertility medications.

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Review Article

Published in 2025, this peer-reviewed chapter details the shift from a glucose-centric to insulin-centric approach in managing PCOS.

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Real Results, Real Change

Explore the outcomes we’ve seen across multiple studies—from weight loss and improved labs to hormonal balance, symptom relief, and fertility breakthroughs.

Weight Loss

Average weight loss of 19 lbs over 8 weeks, including significant reductions in waist and hip circumference.

Weight Loss PILOT Outcomes Weight Loss RCT Outcomes

Insulin Reduction

Insulin levels dropped by over 50% in our pilot and metabolic studies—demonstrating the profound impact of a Low Insulin Lifestyle on insulin resistance.

Insulin Results

A1c Improvement

HbA1c improved significantly from 5.5% to 5.2% in just 8 weeks, with a p-value of <0.0001, showing meaningful improvement in glycemic control.

A1c Improvement

Testosterone

Testosterone levels dropped to within normal ranges, with marked improvements in symptoms like acne and hair growth.

Testosterone Reduction

Symptom Relief

From fatigue and bloating to irregular cycles and acne, participants saw consistent improvement in multiple PCOS-related symptoms.

PCOS Symptom Relief

Fertility

Women previously diagnosed as infertile and obese conceived on average within 86 days—without the use of fertility medication—following a Low Insulin Lifestyle.

Fertility Outcomes