Skip to main content

Learn how Lilli Health is shaping the future of PCOS wellness. Learn More



Insulin and Men’s Reproductive Health

Infertility is a common issue, affecting approximately 1 in 8 couples worldwide. Surprisingly, in about 50% of infertility cases, the male partner plays a significant role. It’s important to recognize that the causes of male infertility can be multifaceted, and one crucial factor that often goes unnoticed is the impact of insulin resistance and high insulin levels. However, men’s reproductive health encompasses more than just fertility. By adopting a low insulin lifestyle and working towards lowering insulin levels, men can improve various reproductive health conditions that affect them.

Erectile Dysfunction

One significant area where insulin resistance and high insulin levels can impact men’s reproductive health is erectile dysfunction (ED). Insulin resistance can impair blood flow, affecting the ability to achieve and maintain an erection. By addressing insulin resistance and lowering insulin levels, men may experience improvements in their erectile function, leading to enhanced sexual performance and satisfaction.

Sperm Health

Furthermore, insulin resistance and high insulin levels have been associated with sperm health issues. Studies have shown that elevated insulin levels can contribute to reduced sperm quality, including decreased motility, abnormal morphology, and reduced sperm count. By adopting a low insulin lifestyle, men can potentially improve their sperm health, increasing the chances of successful conception.

Prostate Health

Prostate health is another aspect of men’s reproductive well-being that can be influenced by insulin levels. Studies have suggested a link between insulin resistance and an increased risk of prostate enlargement (benign prostatic hyperplasia) and prostate cancer. By managing insulin levels through lifestyle modifications, men may reduce their risk and promote better prostate health.

Low Testosterone

Additionally, insulin resistance and high insulin levels can impact testosterone levels in men. Testosterone is a vital hormone for male reproductive health, influencing libido, energy levels, muscle mass, and overall well-being. Insulin resistance can lead to decreased testosterone production or inefficient utilization of testosterone in the body. By adopting a low insulin lifestyle, men may experience improvements in testosterone levels, promoting better reproductive health and overall vitality.

Low Libido

Low libido, or a decreased sex drive, can also be influenced by insulin resistance and high insulin levels. Addressing these factors through lifestyle modifications can help enhance libido, improving the overall sexual experience and satisfaction for men.

By understanding the broader implications of insulin resistance and high insulin levels on men’s reproductive health, we can emphasize the importance of adopting a low insulin lifestyle. This includes making dietary choices that minimize insulin spikes, engaging in regular physical activity, managing stress levels, and getting adequate sleep. These lifestyle modifications can contribute to improved insulin sensitivity, better metabolic health, and enhanced reproductive well-being.

It’s crucial to promote awareness and open discussions surrounding men’s reproductive health, including the impact of insulin resistance and high insulin levels. Encouraging men to seek comprehensive care that addresses the underlying insulin-related issues can lead to better overall reproductive health outcomes. By prioritizing a low insulin lifestyle, men can take control of their reproductive health, improve fertility, enhance sexual function, promote prostate health, boost testosterone levels, and revitalize their overall well-being. 

If you are experiencing reproductive health issues, it’s important to talk to your healthcare provider and ask to have your fasting insulin tested. An ideal fasting insulin should be between 3-8 mIU/ml. Anything higher than 8 mIU/ml suggests insulin resistance. If your healthcare provider says no, you will soon be able to purchase a Lilli at-home insulin testing kit directly from our website! This will allow you to stay on top of your metabolic and reproductive health from the comfort of your own home.



  • Mansour R, El-Faissal Y, Kamel A, et al. Increased insulin resistance in men with unexplained infertility. Reprod Biomed Online. 2017;35(5):571-575. doi:10.1016/j.rbmo.2017.08.020
  • Pitteloud N, Mootha VK, Dwyer AA, et al. Relationship Between Testosterone Levels, Insulin Sensitivity, and Mitochondrial Function in Men.; 2005.
  • Shanik MH, Xu Y, Skrha J, Dankner R, Zick Y, Roth J. Insulin resistance and hyperinsulinemia: is hyperinsulinemia the cart or the horse? Diabetes Care. 2008;31 Suppl 2. doi:10.2337/dc08-s264
  • Abdul-Ghani M, DeFronzo RA. Insulin Resistance and Hyperinsulinemia: The Egg and the Chicken. Journal of Clinical Endocrinology and Metabolism. 2021;106(4). doi:10.1210/clinem/dgaa364
  • Janssen JAMJL. Hyperinsulinemia and its pivotal role in aging, obesity, type 2 diabetes, cardiovascular disease and cancer. Int J Mol Sci. 2021;22(15). doi:10.3390/ijms22157797
  • Pohlmeier AM, Phy JL, Watkins P, et al. Effect of a low-starch/low-dairy diet on fat oxidation in overweight and obese women with polycystic ovary syndrome. Applied Physiology, Nutrition and Metabolism. 2014;39(11):1237-1244. doi:10.1139/apnm-2014-0073
  • Phy Jennifer L, Pohlmeier AM, Cooper JA, et al. Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co- Morbidities Linked to Polycystic Ovary Syndrome (PCOS). J Obes Weight Loss Ther. 2015;05(02). doi:10.4172/2165-7904.1000259
  • Araújo J, Cai J, Stevens J. Prevalence of Optimal Metabolic Health in American Adults: National Health and Nutrition Examination Survey 2009–2016. Metab Syndr Relat Disord. 2019;17(1):46-52. doi:10.1089/met.2018.0105
  • Leisegang K, Bouic PJ, Menkveld R, Henkel RR. Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort. Reproductive Biology and Endocrinology. 2014;12(1):34. doi:10.1186/1477-7827-12-34
  • Chen S, Wu R, Huang Y, et al. Insulin Resistance Is an Independent Determinate of ED in Young Adult Men. PLoS One. 2013;8(12):e83951. doi:10.1371/journal.pone.0083951
  • Grossmann M, Thomas MC, Panagiotopoulos S, et al. Low Testosterone Levels Are Common and Associated with Insulin Resistance in Men with Diabetes. J Clin Endocrinol Metab. 2008;93(5):1834-1840. doi:10.1210/jc.2007-2177
  • Wang L, Lu B, He M, Wang Y, Wang Z, Du L. Prostate Cancer Incidence and Mortality: Global Status and Temporal Trends in 89 Countries From 2000 to 2019. Front Public Health. 2022;10. doi:10.3389/fpubh.2022.811044